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However, they carry side effects and addiction risks. * With 15% L-Dopa (the immediate precursor of dopamine), NOW® Dopa Mucuna helps the body Diet and Exercise: Supplements work best when combined with a healthy diet rich in whole foods, regular exercise, and adequate sleep. The reward system in your brain releases “feel-good” chemicals such as dopamine to signal pleasure in response to a stimulus. We You will also find vitamin B in dopamine supplements, like Life Extension's Dopamine Advantage, which contains a neurologically active form of vitamin B12. dopamine and norepinephrine I am exploring here the best dopamine supplements, dietary and lifestyle changes as well as the medications that increase dopamine. 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